KLIFS - the structural kinase database

Search results (20 entries covering 7 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
Abl1 (ABL1)	Abl	TK	3kfa	A		3-{(e)-2-[6-(cyclopropylamino)-9h-purin-9-yl]ethenyl}-4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide	Mouse	5742	1.00
Abl1 (ABL1)	Abl	TK	3kfa	B		3-{(e)-2-[6-(cyclopropylamino)-9h-purin-9-yl]ethenyl}-4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide	Mouse	5740	1.00
MAPK11 (p38b)	MAPK	CMGC	3gp0	A	B	nilotinib	Human	2764	0.48
MAPK11 (p38b)	MAPK	CMGC	3gp0	A	A	nilotinib	Human	2768	0.48
ABL1	Abl	TK	3cs9	C	A	nilotinib	Human	1046	0.48
EPHA3 (EphA3)	Eph	TK	3dzq	A	A	n-[2-methyl-5-({[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]carbonyl}amino)phenyl]isoxazole-5-carboxamide	Human	2852	0.43
EPHA3 (EphA3)	Eph	TK	3dzq	A	B	n-[2-methyl-5-({[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]carbonyl}amino)phenyl]isoxazole-5-carboxamide	Human	2868	0.43
ABL1	Abl	TK	3cs9	A	A	nilotinib	Human	1080	0.48
ABL1	Abl	TK	5mo4	A	B	nilotinib	Human	7526	0.48
DDR1	DDR	TK	6hp9	B		(2~{r})-~{n}-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-2-(pyrimidin-5-ylamino)-2,3-dihydro-1~{h}-indene-5-carboxamide	Human	10884	0.55
DDR1	DDR	TK	6hp9	A		(2~{r})-~{n}-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-2-(pyrimidin-5-ylamino)-2,3-dihydro-1~{h}-indene-5-carboxamide	Human	10885	0.55
ABL1	Abl	TK	3cs9	B	B	nilotinib	Human	1112	0.48
ABL1	Abl	TK	5mo4	A	A	nilotinib	Human	7527	0.48
ABL1	Abl	TK	3cs9	B	A	nilotinib	Human	1050	0.48
ABL1	Abl	TK	3cs9	C	B	nilotinib	Human	1093	0.48
ABL1	Abl	TK	3cs9	D	B	nilotinib	Human	1066	0.48
ABL1	Abl	TK	3cs9	A	B	nilotinib	Human	1107	0.48
EPHA2 (EphA2)	Eph	TK	8boh	A	A	4-methyl-~{n}-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide	Human	14647	0.50
EPHA2 (EphA2)	Eph	TK	8boh	A	B	4-methyl-~{n}-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide	Human	14651	0.50
ABL1	Abl	TK	3cs9	D	A	nilotinib	Human	1077	0.48